DOLO 500 (Paracetamol (500mg))

DOLO 500 is a popular formulation of Paracetamol, also referred to as Acetaminophen, in India. Each tablet contains 500mg of the active compound. This medication is easily obtainable without a prescription and is primarily utilized for the relief of mild to moderate pain and the reduction of fever. It is essential to distinguish Paracetamol from NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) such as Ibuprofen. Paracetamol is effective in alleviating pain and lowering fever, but it exhibits minimal anti-inflammatory properties. The mechanism by which DOLO 500 operates mainly involves the central nervous system, specifically the brain and spinal cord. It is thought to inhibit the synthesis of specific prostaglandins, which are chemicals that mediate pain and fever responses within the body, thereby decreasing the sensation of pain. Additionally, it acts on the hypothalamus, an area of the brain that regulates body temperature, helping to restore an elevated temperature to normal by promoting heat loss through processes like vasodilation and perspiration. DOLO 500 is indicated for various conditions, including fever from infections such as the flu or bacterial illnesses, and it can also address several types of pain, including headaches, toothaches, muscle discomfort, joint pain, menstrual cramps, sore throat, and post-injury or procedural pain. Responsible usage is critical, as exceeding the recommended dosage may lead to severe consequences, including fatal liver damage.